HW: Alchoholic Beverages? Halt that hangover NOW!

[ANDREW GARIBALDI]

hey - bet Brock's loving this!!!!!!!!
Andy G'b.
----- Original Message -----
From: "flossbac" <flossbac at NLCI.COM>
To: <BOC-L at LISTSERV.SPC.EDU>
Sent: Friday, November 03, 2000 1:11 AM
Subject: Re: HW: Alchoholic Beverages? Halt that hangover NOW!


> > I loved that bit of info from Doug Pearson about the 'Turkey Effect'.
Xmas
> > dinner will never seem quite the same again!
> >
> > Now.....how many of you out there remember as a teenager, being able to
go
> > out and consume a sufficient excess of alchohol......sleep it
off.....and
> > wake up feeling fine (albeit a bit dehydrated) and well enough to go to
> > school or college?
> >
> > The as time rolls on into your 20's (when I got my first REAL
> > hangover)....then into the 30's and you go out and drink moderately
> without
> > getting plastered and you wake up the following morning feeling  worse
> than
> > shite itself.  And the problem gets worse with age.
> >
> > Well .....there is a preventative answer.......which does not involve
> > drinking pints of milk to line the stomach or consuming vast quantities
of
> > water at the end of your night out.
> >
> > Some years ago the owner of an off licence suggested doing exactly what
> all
> > the doctors and nurses do before they go on their ritualistic binge
after
> a
> > hard weeks shift......
> > Very simple........you swallow 2 Ibuprofen tablets (ie Neurofen in the
UK)
> > (*NOT PARACETAMOL OR ASPIRIN!!!!*)
> > It has to be Ibuprofen painkiller/anti inflammatory....taken as
> > directed,preferably with food....BEFORE YOU START DRINKING!
> >
> > I've tried it on numerous occasions and it really does
work...........BUT
> > HOW????
> >
> > I met up with a consultant from Guys Hospital in London some time ago,
and
> > asked him about this just to find out if he could authenticate this
> > preventative remedy.
> > He was well familiar with this pre-hangover treatment and went on to
> > explain exactly how it works.
> > It is nothing to do with 'killing the pain in advance'.
> > What happens is.....(as I recall).......By taking Ibuprofen before
> > consuming alcholic drink,
> > the alchohol reacts with the Ibuprofen in the stomach, and produces an
> > enzyme which in turn,neutralises the antibodies within the alchoholic
> > drink, that would otherwise go on to give you a 'hangover'.
> > It's actually helping to do exactly what our livers did for us as
> teenagers
> > when we went out drinking.
> > Unfortunately.......as we get older, our livers become less efficient at
> > dealing with this type of abuse,which is why 43 yr old 'lightweights'
such
> > as myself feel shitty the morning after just 2 and a half pints of
> Guiness.
> >
> > Like I said before....IT MUST BE IBUPROFEN
> >                 AT THE PRESCRIBED DOSAGE
> >                 TAKEN WITH FOOD !
> >
> > NOT Paracetamol - NOT Panadol - NOT Aspirin !!!!! ( or any other
> painkiller
> > bought over the counter! )
> > Mel
>
>
> OK as regards alcohol and hangovers... the cause of the yucky feelings in
a
> hangover is dehydration of the central nervous system.  The best way to
> avoid a hangover has been and always will be to drink lots of water (not
> more alcohol, and not caffeine-containing substances, as both of these are
> dehydrating).  So drink lots of water before, during, and after your
> drinking binge and you should feel a lot better.
>
> As regards ibuprofen... I can't see any reason why it would be an
effective
> preventative for a hangover.  It MIGHT be possible that ibuprofen has a
> small inducer effect on liver enzymes, which could speed the metabolism of
> alcohol, but the effect is probably negligible, as it is pretty well known
> which drugs and which drug classes are inducers and inhibitors of the P450
> system of liver enzymes (the ones that generally metabolize drugs etc. in
> the body), and ibuprofen is neither an inducer or inhibitor according the
> research.  As for the proposed hypothesis about antibodies in alcohol
etc...
> that's just a garbled mess of misinformation.  Antibodies are produced by
> the immune system in response to foreign invaders.  Alcohol doesn't have
> antibodies.  My personal opinion is that if there is any effect from
> ibuprofen to prevent hangovers, I think it is all psychosomatic.
>
> John Majka
> flossbac at nlci.com